Board-certified dermatologists Dr. Ronald C. Knipe and Dr. Samantha A. Marrone, together with our dermatology-certified nurse practitioners and physician assistant, have cared for patients in greater Orlando for more than 30 years.
Downtown Dermatology specializes in dermatological surgery and the treatment of general dermatological skin conditions. Our board-certified physicians and licensed providers care for patients across every age and every concern — from pediatric rashes and teenage acne to adult skin cancer screenings and cosmetic rejuvenation.
We practice traditional medical dermatology with a modern standard of care: unhurried appointments, direct physician involvement, and attention to detail.
Medical, surgical and cosmetic dermatology — all performed in our office by board-certified physicians and licensed providers.
Comprehensive diagnosis and treatment for common and complex skin conditions, from infants to seniors.
Minimally invasive removal of growths and suspicious lesions, performed by our board-certified physicians and licensed providers.
Evidence-based cosmetic dermatology — natural, refined results administered by experienced providers.
Two physicians, two advanced-practice registered nurses, and a physician assistant — caring for Central Florida skin together.

Dr. Knipe has practiced dermatology in Orlando for more than 30 years, with a warm, detailed, patient-first approach.
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Dr. Marrone partners with Dr. Knipe to care for patients, providing medical, surgical, and cosmetic care with a focus on skin cancer detection and minor surgical procedures.
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Dermatology-certified nurse practitioner working alongside the physicians across the full range of medical dermatology care.
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Dermatology-certified nurse practitioner providing comprehensive medical and cosmetic dermatology care.
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Physician assistant specializing in dermatology, partnering with the practice's physicians to deliver thorough, attentive patient care.
Read full bio →From the front desk to the treatment room, our staff is the reason patients have stayed with us for decades. Bilingual English and Spanish service. Trained. Personable. Long-tenured.
We're a private, independent practice. You see an experienced licensed provider. You're not rushed. And your chart doesn't get lost in a corporate system.
Dr. Knipe and Dr. Marrone set provider training and daily protocol.
Medical, surgical, and cosmetic — all performed in-office.
Most major insurance plans accepted for covered medical visits.
Central Orlando location with parking. Bilingual EN / ES staff.
Please fill out the forms, print them and bring to your appointment. If you do not have Adobe, you can fill out the forms in the office.
NOTE: Both forms can be filled in on screen — click on the areas you wish to fill out and start typing, then print.
Your contact details, insurance information and consent to treat. This form can be typed directly in your browser or in Adobe Reader, then printed.
Medications, allergies, skin history and past conditions. This form can be typed directly in your browser or in Adobe Reader, then printed.
Please call the office to verify your specific plan and coverage. Cosmetic services are typically not insurance-covered.









We recommend that you contact your insurance company to verify we are providers of your specific plan.
Patients have been coming here for over 30+ years. Many were referred by family members and friends.
Read patient reviews →Central downtown location, just south of Orlando Health and Lake Lucerne.
70 W Gore Street, Suite 200A
Orlando, FL 32806