Board-Certified · Serving Orlando 25+ Years

Expert skin care, right here in downtown Orlando.

Board-certified dermatologists Dr. Ronald C. Knipe and Dr. Samantha A. Marrone, together with our dermatology-certified nurse practitioners and physician assistant, have cared for patients in greater Orlando for more than 25 years.

Dr. Ronald C. Knipe, MD, board-certified dermatologist at Downtown Dermatology Orlando
Dr. Ronald C. Knipe, MD
Board-Certified Dermatologist · Founder
25+
Years in Orlando
5
Board-Certified Providers
4.4 ★
Patient Rating
All Ages
Pediatric to Geriatric
Downtown Dermatology reception area in Orlando, FL

A private Orlando practice specializing in skin.

Downtown Dermatology specializes in dermatological surgery and the treatment of general dermatological skin conditions. Our board-certified physicians and licensed providers care for patients across every age and every concern — from pediatric rashes and teenage acne to adult skin cancer screenings and cosmetic rejuvenation.

We practice traditional medical dermatology with a modern standard of care: unhurried appointments, direct physician involvement, and attention to detail.

Full-spectrum skin care, under one roof.

Three integrated service lines, all delivered in-office by board-certified physicians and licensed providers.

General & Pediatric

Medical dermatology for every age

Comprehensive diagnosis and treatment for common and complex skin conditions, from infants to seniors.

  • Acne & rosacea
  • Eczema & atopic dermatitis
  • Psoriasis
  • Contact dermatitis
  • Melasma & pigmentation
  • Pediatric skin conditions
  • Skin cancer screenings
Surgical

In-office dermatologic surgery

Minimally invasive removal of growths and suspicious lesions, performed by our board-certified physicians.

  • Mole & lesion removal
  • Skin tag removal
  • Cyst & lipoma excision
  • Wart treatment
  • Biopsies of suspicious growths
  • Skin cancer excisions
Cosmetic

Rejuvenation & cosmetic treatments

Evidence-based cosmetic dermatology — natural, refined results administered by experienced physicians.

  • Botox® wrinkle reduction
  • Juvéderm & dermal fillers
  • Chemical peels
  • Brown spot treatment
  • Skin texture & tone
  • Anti-aging consultations

Five board-certified providers. One focused practice.

Two physicians, two advanced-practice registered nurses, and a physician assistant — caring for Central Florida skin together.

Dr. Ronald C. Knipe, MD

Dr. Ronald C. Knipe, MD

Board-Certified Dermatologist · Founder

Dr. Knipe has practiced dermatology in Orlando for more than 25 years, providing medical, surgical, and cosmetic care with a focus on skin cancer detection and minor surgical procedures.

Dr. Samantha A. Marrone, MD

Dr. Samantha A. Marrone, MD

Board-Certified Dermatologist

Dr. Marrone partners with Dr. Knipe to care for patients across every dermatologic need — medical, surgical, and cosmetic — with a warm, detailed, patient-first approach.

@samtheskindoc →
Amy K. Wells, APRN

Amy K. Wells, APRN

Advanced-Practice Registered Nurse

Dermatology-certified nurse practitioner working alongside the physicians across the full range of medical dermatology care.

Jennifer B. Blattner, APRN

Jennifer B. Blattner, APRN

Advanced-Practice Registered Nurse

Dermatology-certified nurse practitioner providing comprehensive medical and cosmetic dermatology care.

@jenthedermnp →
Alison Tessitore, PA-C

Alison Tessitore, PA-C

Certified Physician Assistant

Physician assistant specializing in dermatology, partnering with the practice's physicians to deliver thorough, attentive patient care.

Behind every appointment, a full team.

From the front desk to the treatment room, our staff is the reason patients have stayed with us for decades. Bilingual English and Spanish service. Trained. Personable. Long-tenured.

Downtown Dermatology staff team photo

Your skin deserves a specialist, not a production line.

We're a private, independent practice. You see a physician. You're not rushed. And your chart doesn't get lost in a corporate system.

Physician-led care

Direct involvement from Dr. Knipe and Dr. Marrone on every case.

Full-spectrum service

Medical, surgical, and cosmetic — all performed in-office.

Insurance friendly

Most major insurance plans accepted for covered medical visits.

Downtown convenient

Central Orlando location with parking. Bilingual EN / ES staff.

Most major plans accepted for medical dermatology.

Please call the office to verify your specific plan and coverage. Cosmetic services are typically not insurance-covered.

AARP
Aetna
Anthem Blue Cross
AvMed
Cigna
Humana
Medicare
Orlando Health
Tricare
+ more
Call to verify

Additional plans accepted including Allegiant, Assurant, GEHA, Golden Rule, Great West / Cigna, Cigna Healthspring, and VA. Call (407) 581-2888 to verify yours.

★★★★★
4.4 / 5
Across patient reviews on Yelp, Google, Healthgrades and WebMD

Orlando trusts Downtown Dermatology.

Patients have been coming here for 10, 15, even 20+ years. Many were referred by family members and friends.

Read patient reviews →

70 West Gore Street, Orlando, FL.

Central downtown location, just south of Orlando Health and Lake Lucerne.

Downtown Dermatology

70 W Gore Street, Suite 200A
Orlando, FL 32806

Fax(407) 481-0073
Monday – Thursday8:00 AM – 5:00 PM
Friday8:00 AM – 12:00 PM
Saturday & SundayClosed
Get directions → Call (407) 581-2888
70 W Gore Street, Downtown Dermatology office location in Orlando, FL
Proudly Affiliated With
Shepherd's Hope Grace Medical Home Orlando Regional Medical Center Community Services

Ready to take care of your skin?

Call our office to book with Dr. Knipe, Dr. Marrone, or one of our advanced-practice providers.